The GABAergic Gudden’s dorsal tegmental nucleus: a new relay for serotonergic regulation of sleep-wake behavior in the mouse.
Chazalon M., Dumas S., Bernard J.-F., Sahly I., Tronche F., deKerchove d’Exaerde A., Hamon M., Adrien J., Fabre V.*,  Bonnavion P.* Neuropharmarcology, 138:315-30, 2018. *co-last authors. 
Identification of a new circuit underlying serotonergic arousing effects through the GABAergic Gudden dorsal tegmental nucleus directly connected to wake centers in the posterior hypothalamus.
DOI: 10.1016/j.neuropharm.2018.06.014 

Hypothalamic Tuberomammillary Nucleus Neurons: Electrophysiological Diversity and Essential Role in Arousal Stability.
Fujita A.*, Bonnavion P.*#, Wilson M.H., Mickelsen L.E., Bloit J., de Lecea L., Jackson A.C. Journal of Neuroscience, 37: 9574-92, 2017. *co-first, #co-corresponding authors. 
Proof-of-concept that TMN histamine neurons are necessary for arousal maintenance and that their inhibition is sufficient to elicit sleep.
DOI: 10.1523/JNEUROSCI.0580-17.2017 

Antagonistic interplay between hypocretin and leptin in the lateral hypothalamus regulates stress responses.
Bonnavion P.,  Jackson A.C., Carter M.C., de Lecea L. Nature Communication. 6: 6266, 2015. 
Sustained activation of hypothalamic hypocretin system in metabolic disbalance drives aversive hyperarousal and generalized stress controlled by a local GABAergic circuit involving leptin brain signaling. Relevance to new therapeutic strategies involving hypocretin and leptin in anxiety-related eating disorders and panic attacks (NARSAD Young Investigator prize).
DOI: 10.1038/ncomms7266 

A mechanism for Hypocretin-mediated sleep-to-wake transitions. 
Carter M.E., Brill J., Bonnavion P.,Huguenard J.R., Huerta R., de Lecea L. Proceedings of the National Academy of Sciences. USA. 109(39): 2635-44, 2012. 
LC noradrenergic neurons activation by hypothalamic hypocretin is necessary to promote and maintain arousal.
DOI: 10.1073/pnas.1202526109 

Heterogeneous distribution of the 5-HT1A receptor mRNA in chemically identified neurons of the mouse rostral brainstem.
Bonnavion P., Bernard J.-F., Hamon M., Adrien J., Fabre V. Journal of Comparative Neurology. 518(14): 2744-70, 2010. 
Evidence that waking serotonergic raphe nuclei are highly heterogeneous targeting predominantly pontine GABAergic cells and demonstrating that, contrary to the canonical dogma, 5-HT neuronal subsets are differentially regulated by negative feedback loop (Albert Sezary Prize).
DOI: 10.1002/cne.22331 

Book Chapters & Reviews:

Serotonin and Sleep.
Fabre, V., Krystal, A. & Bonnavion, P. Principles and Practice of Sleep Medicine, 7th edition. Dement, W.C., Kryger M.H., Roth T. (Eds). Elsevier. (in press)

It takes two to tango: Dorsal direct and indirect pathways orchestration of motor learning and behavioral flexibility. 
Bonnavion,  P., Pozuelo Fernandez,  E., Varin,  C., de Kerchove d’Exaerde,  A. Neurochemistry international, 124, 200-214, 2019. 
DOI: 10.1016/j.neuint.2019.01.009 

Pharmacosynthetic Deconstruction of Sleep-Wake Circuits in the Brain. 
Varin,  C. & Bonnavion,  P. Handbook of experimental pharmacology, 253, 153-206, 2019.
DOI: 10.1007/164_2018_183 

Hubs and spokes of the lateral hypothalamus: cell types, circuits and behaviour. 
Bonnavion,  P., Mickelsen,  L.  L., Fujita,  A., De Lecea,  L., & Jackson,  A.  A. (2016). Journal of physiology, 594(22), 6443-6462, 2016.
DOI: 10.1113/JP271946