New submitted paper on the role of D1- and D2-SPNs in social interaction is now in BioRxi
Our study reports the key role played by NAc D1R/D2R-SPN balance of activity in controlling social behavior and evidences the promises of pharmacological compounds developed to repress D2R. https://biorxiv.org/cgi/content/short/2022.11.28.518147v1
New submitted paper on a new epigenetic mechanism in drug addiction is now in bioRxiv
We have identified a novel cocaine-induced epigenetic mechanism in the thalamus relevant to cocaine use disorders in humans. https://www.biorxiv.org/content/10.1101/2022.11.16.516716v1
A lipid transfer protein ensures nematode cuticular impermeability
At the origin of many discoveries, the nematode C. elegans has forged a solid reputation as a genetic model organism. Its use as a pharmacological model is however limited: its cuticle is impermeable to chemicals, toxins and pathogens. Increased permeability is therefore a desirable phenotype as it would facilitate chemical absorption. We identified a mutant […]
New submitted paper on motor encoding in the striatum is now in bioRxiv
Our work highlights a complementary encoding of behaviors in the two striatal pathways that supports an updated model, reconciling previous conflicting conclusions on motor encoding in the striatum. https://doi.org/10.1101/2022.06.20.496781
Congratulations to Alban de Kerchove d’Exaerde for the awarded WELBIO+CDR+EQP+PDR FNRS research grants!
Congratulations to Alban de Kerchove d’Exaerde for the awarded WELBIO+CDR+EQP+PDR FNRS research grants!
New paper release highlighting an unexpected paradoxical motor inhibition by dopamine in the striatum
Unexpected inhibition of motor function by dopamine activation of D1/D2 co-expressing striatal neurons. https://doi.org/10.1101/2022.04.05.487163 https://www.biorxiv.org/content/10.1101/2022.04.05.487163v1
Congratulations to Patricia Bonnavion & Serge Schiffmann for the awarded MIS & PDRFNRS research grants!
Congratulations to Patricia Bonnavion & Serge Schiffmann for the awarded MIS & PDR FNRS research grants! We are hiring
paper release on Extracellular Vesicle release in C. elegans
Ectocytosis prevents accumulation of ciliary cargo in C. elegans sensory neurons. DOI: 10.7554/eLife.67670
New Review on drug addiction
Drug addiction: from bench to bedside. Read the full article here
Paper release on striatal functions in sexual behavior
Dorsal and ventral striatal neuronal subpopulations differentially disrupt male mouse copulatory behavior. DOI: 10.1016/j.euroneuro.2021.03.007
